Organophosphates and carbamates enter an organism through respiration, ingestion, and skin, inhibiting the activity of the cholinesterase enzyme in the transmission of nervous impulses in the autonomic nervous system and causing cholinergic muscarinic manifestations such as excessive salivation, lacrimation, excessive urination, diarrhea, vomiting (emesis), bronchorrhea, rhinorrhea, bronchospasm, bradycardia, and miosis. This evidence concerns the gene BCHE and Miosis.