Hydrodynamic tail vein injection (HTVi) was used to induce HCC tumorigenesis, and protooncogenes (myr‐AKT1 and N‐RASG12V) were coinjected with scr, shIGF2BP3, shIGF2BP3+rIGF2BP3WT, or shIGF2BP3+rIGF2BP3K76R plasmids (Figure 2F). Here, AKT1 is linked to hepatocellular carcinoma.