The susceptibility single nucleotide polymorphisms (SNPs) associated with familial NB in genome-wide association studies (GWAS) include: BARD1, DUSP, DDX4-IL31RA, HACE1, HSD17B, LMO1, LIN28B, LINC00340, and LOC729177 (FLJ44180) (32–35). The gene discussed is HACE1; the disease is neuroblastoma.