PTGES and lung carcinoma: The hub targets of ROB action in lung cancer were further analyzed by combining 14 targets from Degree≥6, 10 targets each from MCC and MNC algorithms, and finally 7 common targets such as PTGS2, CYP19A1, PTGS1, AR, CYP17A1, PTGES and SRD5A1 were obtained from the final screening (Figure 3B).