Candesartan, Benazepril, Valsartan, Eprosartan, Olmesartan Medoxomil, Telmisartan, Irbesartan, Captopril and Perindopril are commonly used angiotensin-converting enzyme inhibitor (ACEI) or angiotensin receptor antagonist (ARB), which can be used to treat cardiovascular diseases such as hypertension and heart failure (55–63). This evidence concerns the gene ACE and heart failure.