GSDMD and rheumatoid arthritis: (292) found that the proportion of pyroptosis and LDH activity were reduced, and the expression of caspase-1/3/4/5 and GSDMD were decreased in mice treated with Jinwu Jianjian Bone Capsules (JWJGC)-containing serum, suggesting that JWJGC improves the tumor-like growth characteristics of RA-FLS by inhibiting cellular pyroptosis and suppressing its proliferation in RA treatment.