BRCA1 and breast cancer: For women carrying BRCA1 sequence variants, the breast cancer mortality rate associated with MRI surveillance programs was 0.20 (95% CI, 0.10-0.43; P < 0.001), and for those carrying BRCA2 sequence variations, it was 0.87 (95% CI, 0.10-17.25; P = 0.93) (Figure 3) [48]. ​​