Herein, we present a unique case of acromegaly due to a GHRH-secreting lung NET (bronchial carcinoid) causing enlargement of the pituitary gland, pituitary apoplexy, tumoral range hyperprolactinemia with remarkable resolution of clinical features hyperprolactinemia and IGF-1 levels after resection of the primary lung tumor. The gene discussed is GHRH; the disease is hyperprolactinemia.