TGFB1 and familial dilated cardiomyopathy: Finally, the following plasma exosomes of DCM patients with HF were found to be dysregulated: hsa-miRNA-3138_L-5R+2, which controls cardiac mitochondrial activity; hsa-miRNA-1304-3p_1ss13CA, which is implicated in inflammation and oxidative stress; and hsa-miRNA-10a-5p_R-1, which is linked to cardiac fibrosis via the TGF-β/Smad3 signaling pathway [88].