In this regard, it has been shown that, while Cd induces the epithelial–mesenchymal transition (EMT) in CRC cell lines, RES could prevent Cd-induced migration and invasion of CRC cells in vitro by controlling the m6A alteration of zinc finger E-box binding homeobox 1 (ZEB1) and the expression of EMT-related markers [127]. This evidence concerns the gene ZEB1 and colorectal carcinoma.