In the mice study, it was observed that, when the red seaweed was given to HF-diet-induced obese mice for 13 weeks, the HF diet supplemented with 2% C. hypnaeoides and 6% C. hypnaeoides reduced body weight, decreased insulin resistance, decreased adiponectin, and increased malondialdehyde (MDA), tumor necrosis factor α (TNF-α), and monocyte chemoattractant protein-1 (MCP-1) [41]. The gene discussed is CCL2; the disease is hydrops fetalis.