Sickle cell disease (SCD) is one of the most common inherited disorder worldwide [1,2] characterized by the presence of Hb S, from either homozygosity (Hb S/S) or compound heterozygosity, with another β globin variant (e.g., S/β0-thalassemia, S/βþ-thalassemia, S/O-Arab, S/D-Punjab, S/C disease) [3]. The gene discussed is GSTM1; the disease is thalassemia.