A deeper understanding of the etiology and pathogenetic mechanisms of GFAP astrocytopathy is still lacking; however, it often coexists with a malignancy (most commonly ovarian teratoma), anti-neuronal and anti-glial autoantibodies, while a link between viral infection and GFAP astrocytopathy has also been reported in several case series [1,2,3,4,5,6,7]. This evidence concerns the gene GFAP and ovarian teratoma.