Uni‐ and multivariate analyses showed that the SII, PLR, mGNRI, creatinine and SI, but not ALI, NLR, CRP, CAR, LCR, IBI, AGR, PNI, GLR, GNRI, NRI and cystatin C, were independent predictive factors for ALS survival (Table 2). This evidence concerns the gene CST3 and amyotrophic lateral sclerosis.