In GN, B3GALT4 exhibited notably high expression levels, while ST8SIA1 displayed relatively lower expression levels when compared to NB supporting our previous finding suggesting the expression of the a-series and of complex gangliosides in more differentiated tumors (Fig. S3) Moreover, we observed a strong negative correlation between the gene expression of MYCN and B3GALT4 (r = -0.92) (Fig. 6B), as well as a strong positive correlation between MYCN and ST8SIA1 (r = 0.89) (Fig. 6C). Here, ST8SIA1 is linked to ganglioneuroma.