GPR160 and Anxiety: Beyond evoked nociceptive hypersensitivity, the administration of AAV2/9-Gpr160 into the DRG also elicited anxiety-like behavior during evoked responses, indicated by the open-field test (specifically, a reduced duration of time spent and diminished distance traveled within the central area), as compared to AAV2/9-Gfp treated rats (Fig. EV4M–O).