To investigate the functions of HCP5‐132aa in GC tumorigenesis, we employed CRISPR/Cas9 technology to construct stable knockout of HCP5‐132aa in MKN‐45 and NCI‐N87 cells, while stably overexpressed HCP5‐132aa in HGC‐27 cells (Figure S2A,B, Supporting Information). The gene discussed is HCP5; the disease is gastric cancer.