TPSG1 and major depressive disorder: Finally, in women, the SB(+)/TRPA(–) group (1.61 [1.28–2.03]) and, in men, the SB(+)/TRPA(+) (2.13 [1.39–3.28]) and SB(+)/TRPA(–) groups (1.83 [1.28–2.61]) had significantly increased risk for depression.