Our patient cohort consisted not only of patients with common variable immunodeficiency (CVID), but also of individuals with monogenetic mutations such as X‐linked agammaglobulinemia (XLA), autoinflammatory syndromes, rare mutations like a mutation in the interferon gamma receptor 1 (IFNGR1) gene and a patient with warts, hypogammaglobulinemia, immunodeficiency, myelokathexis (WHIM) syndrome. This evidence concerns the gene IFNGR1 and common variable immunodeficiency.