NEFL and ocular melanoma: Neurofilament light chain (NfL), a major component of the neuronal cytoskeleton that is released into the extracellular space and further into the cerebrospinal fluid (CSF) and the blood after neuroaxonal damage, was used as OM in 68 studies (57 soluble NfL, 19 CSF NfL) comprising 18,131 pwMS, with 34 conducted within RW.