Due to the low number of patients, however, the genes identified from TCGA were confirmed via the All of Us database to identify "candidate genes," and these candidate genes underwent gene expression analysis to identify the gene FBXW7. Gene FBXW7 is a crucial part of the proteasome (protein destruction) system and is in charge of the destruction of important oncogenic (cancer-causing) proteins [25]. The gene discussed is FBXW7; the disease is cancer.