On analyzing the expression of the cytokines IL-6, TNF-α, IL1-β, and IL-10 (Figure 5), a significant decrease in thelevel of cytokine IL-10 was observed in the cells treated with 252 μg/mL of thevenom compared to untreated cells in RA patients and healthy controls (Figure 5 D ). The gene discussed is IL6; the disease is rheumatoid arthritis.