The results showed that CeD was linked to an increased expression of plasma IL-6 (β: 0.038 95% CI: 0.002–0.073, p=0.037) and IL-18 (β: 0.066, 95% CI: 0.018–0.114, p=0.007; Supplementary Table S7). This evidence concerns the gene IL18 and cranioectodermal dysplasia.