IL15 and Sepsis: There are several primary approaches for immunotherapy of sepsis in current research and clinical practice: Cytokine therapy, some cytokines such as granulocyte‐macrophage colony‐stimulating factor (GM‐CSF), IFN‐γ, IL‐7, and IL‐15, can modulate immune cell functions and assist in reversing the immunosuppressive state in septic patients.