,5,13,16 Anti-inflammatory Mφs are characterized by higher clearance and inflammation resolution capacity, together with other immune markers assessed in this study, such as CD206, CD163,6 and CD169,3,4,8 all decreased in CAD patients’ pericardial Mφ and buffy coat-derived Mφ exposed to PF-CAD-sEV in vitro. Here, SIGLEC1 is linked to coronary artery disorder.