Profiling of human PF macrophages showed that CAD patients have a reduced population of anti-inflammatory CD36+/high (Figure 1A), CD206+/high (Figure 1B), CD163+ (Figure 1C), and CD169+ (Figure 1D) cells (CAD vs non-CAD, P < 0.05) (Figure 1). Here, SIGLEC1 is linked to coronary artery disorder.