In addition, activation of transient receptor potential anchor protein 1 (TRPA1) expressed in the cardiovascular system induces inflammation and oxidative stress, which in turn leads to the formation of COVID-19 sequelae (Zhao et al., 2023), and blockade of TRPA1 reduces the expression of pro-fibrotic cytokines and ameliorates cardiac fibrosis (Wang et al., 2018). Here, TRPA1 is linked to COVID-19.