The largest numerical differences between SLE and HD were observed in CD14+ and nonCD19-nonCD14 cell populations with lower proportion of nonCD19-nonCD14 (64.1 %, 95%CI [60.3–67.1] in SLE vs 71.6 % 95%CI [68.7–73.8] in HD, p < 0.0001) and a higher proportion of CD14+ cells in SLE (28.55 % 95%CI [24.4–32.10] in SLE vs 17.95 % 95CI [16.6–20.6], in HD, p < 0.0001) (Fig. S1E). Here, CD14 is linked to Huntington disease.