Several studies have suggested that GAS5 is implicated in numerous types of cancer, such as leukemia, breast cancer, liver cancer, and lung cancer, as well as autoimmune diseases such as pediatric patients affected by inflammatory bowel disease (IBD) (Ji et al., 2022; Yang et al., 2022; Zhang et al., 2019; Lucafò et al., 2019). Here, GAS5 is linked to inflammatory bowel disease.