S100A12 expression was positively correlated with the abundance of naive B cells (r = 0.266, P < 0.001), eosinophils (r = 0.379, P < 0.001), M0 macrophages (r = 0.586, P < 0.001), M1 macrophages (r = 0.287, P < 0.001) and Tregs (r = 0.159, P < 0.05) in sepsis. This evidence concerns the gene S100A12 and Sepsis.