To compare the Immunoscore cutoff methods in matched biopsies and resections, a similar Immunoscore was created with the CD8 and FOXP3 T-cell density in the tumor center of the resections using the cutoffs that were published previously.7 In the matched biopsies and resections, a statistically significant difference in CSS was observed between the lowest and highest Immunoscore groups (Supplemental Figure S4). The gene discussed is FOXP3; the disease is neoplasm.