Besides, our study currently lacks in vivo evidence; however, related research from our group indicates that the knockout of MT1 exacerbates the loss of dopaminergic neurons and motor dysfunction in a PFF‐induced pathological mouse model of PD, which suggests that MT1 plays a critical role in the neurodegenerative processes associated with PD [59]. The gene discussed is MTNR1A; the disease is Parkinson disease.