USP10 and neoplasm: This was further validated using single cell sequencing data from two individual datasets, which demonstrated a tumour-specific increase in USP10 expression when compared to non-transformed, normal tissue (Supplementary Fig. S1g) as well in spatial transcriptomic data from a publicly available dataset (https://www.10xgenomics.com/datasets/visium-hd-cytassist-gene-expression-libraries-of-human-crc, Supplementary Fig. S1 extended).