There were significant differences between preoperative SII and CRP, NLR, PLR, LMR, postoperative recurrence, pathological type and AJCC stage (P < 0.05), but there was no significant differences between SII and age, gender, diabetes, hypertension, BMI, platelet, hemoglobin, tumor size, Ki-67, tumor necrosis, positive surgical margin, surgical mode and Fuhrman grade (P > 0.05). The gene discussed is MKI67; the disease is diabetes mellitus.