However, dysregulation of other signaling pathways reported in NPC cells such as PI3K/Akt-GSK-3β-NF-κB [39] or mTORC1 [40], would contribute as well and may explain why the reduction on protein synthesis observed after mGluR5 inhibition does not reach statistical significance. Here, NFKB1 is linked to nasopharyngeal carcinoma.