Our findings revealed that AAV9-Cebpa vector administration led to increased levels of Cebpa and Acsl4 mRNA (Fig. 5A), accompanied by elevated levels of urea nitrogen (Fig. 5B), serum creatinine (Fig. 5C), UACR (Fig. 5D), and MDA concentration (Fig. 5E) in DKD mice. The gene discussed is ACSL4; the disease is diabetic kidney disease.