Similarly, a study conducted by Oniki et al. reported that carrying of the GSTM1 null genotype, the GSTP1 A/B or B/B genotype, and the GSTA1 A/B or B/B genotype is associated with higher risk for MASLD development, as these genotypes show lower substrate affinity or lower hepatic expression compared to wild-type genotypes (Oniki et al. 2013). The gene discussed is GSTM1; the disease is metabolic dysfunction-associated steatotic liver disease.