In contrast, measurement of hepatic SOD1 gene expression showed that the mRNA level of liver SOD1 was significantly decreased in subjects with cirrhosis secondary to MASH as compared to subjects with cirrhosis secondary to primary biliary cirrhosis as well as with healthy controls, respectively (Sreekumar et al. 2003). The gene discussed is SOD1; the disease is metabolic dysfunction-associated steatohepatitis.