Regarding mRNA expression, gene expression of GPx1 was reported to display an increase in the liver of AMLN as well as HFD-fed mice (Boland et al. 2018; Du et al. 2016); in addition, mRNA expression of GPx7 was significantly upregulated in mice suffering from MASH fibrosis as compared to healthy controls as well as mice with simple steatosis (Kim et al. 2020). The gene discussed is GPX1; the disease is metabolic dysfunction-associated steatohepatitis.