Genetic auditory synaptopathies generally only cause deafness, such as mutations in the CACNA1D gene encoding the CaV1.3L-type Ca2+ channel, the OTOF gene encoding Otoferlin, the SLC17A8 gene encoding Vglut3, and the DIAPH3 gene encoding formin 3. The gene discussed is CACNA1D; the disease is deafness.