ANGPT2 and atherosclerosis: Ahmed et al. reported that Ang-2 inhibits atherosclerosis by limiting LDL oxidation over a nitric oxide-dependent pathway by stimulating the release of nitric oxide from endothelial cells.32 David et al. reported that elevated Ang-2 was an indicator of atherosclerosis in dialysis patients and that Ang-2 was not a marker of atherosclerosis in renal transplantation, attributing this to the disappearance of atherosclerotic changes after renal transplantation.33