We also identified 1 patient with a clinical phenotype typical of AQP4-IgG seropositive NMOSD with high-titer AQP4-IgG seropositivity who was concurrently borderline seropositive for MOG-IgG (a likely false positive), highlighting the value of scrutinizing clinical phenotypes together with assay specificity/sensitivity to make the correct diagnosis in patients with myelitis.21,22,44 Of interest, 1 patient with MOGAD had anti–TNF-α exposure at the time of their myelitis. The gene discussed is AQP4; the disease is myelitis.