ERCC6L2 and bone marrow failure syndrome: ERCC6L2 ranks 26th overall, and it appears to be involved in DNA repair processes,60 with recessive protein null mutations being associated with bone-marrow-failure syndrome.61 It also possesses two domains that commonly occur in known TSGs: the Helicase_C domain is found in nine well-established TSGs, and the SNF2-rel_dom domain is found in three.