Using the criterion of “Degree > 4.870”, we identified 8 key targets of H. cordata against NSCLC, as shown in Figs. (3c and 3d): IL6, MMP9, PPARG, ICAM1, SELE, MMP3, MMP1, and ALOX5. This evidence concerns the gene ALOX5 and non-small cell lung carcinoma.