Greater SCD was associated with lower CSF Aβ42 (β = −3.34, p = 0.003) and Aβ42/40 (β = −0.004, p = 0.004) but was not associated with CSF levels of tau, p‐tau, and NfL (p‐values >0.38). This evidence concerns the gene NEFL and Schnyder corneal dystrophy.