Similarly, the CDD can predict five proved metabolic factors (acetoacetate,[26] glucose,[27] albumin,[28] free cholesterol,[29] and fatty acid length[30]) for the Alzheimer's disease (Figure 5b and Table S5, Supporting Information), and the Mendelian randomization can only predict one proved risk factor (Esterified cholesterol[31]) for the Alzheimer's disease (Figure 5e and Table S6, Supporting Information). The gene discussed is ALB; the disease is early-onset autosomal dominant Alzheimer disease.