In contrast, our algorithm successfully identified a significant relationship between glut4 and chronic kidney disease, aligning with the findings reported in the published article.[34] The study suggests that the downregulation of glut4 in skeletal muscle may be associated with insulin resistance in chronic kidney disease.[34] The confirmed relationship between glut4 and chronic kidney disease further supports the effectiveness and reliability of our algorithm in uncovering meaningful associations. This evidence concerns the gene SLC2A4 and Insulin resistance.