YTHDF3 promotes the translation of m6A-modified mRNAs of breast cancer brain metastasis-associated genes (e.g., ST6GALNAC5, GJA1, and EGFR) by recruiting eIF3a and increasing the expression of the corresponding proteins, which ultimately affects the brain metastasis of breast cancer 46. This evidence concerns the gene ST6GALNAC5 and breast carcinoma.