Subsequently, the ccRCC cell lines were transfected with control-si, siMYH9, PCDH-CMV-coGFP, SP3-461aa-FLAG, or SP3-461aa-FLAG + siMYH9, followed by the assessment of their proliferation, migration, and invasion capabilities (Figure 10A-C). This evidence concerns the gene SP3 and nonpapillary renal cell carcinoma.