Quercus leucotrichophora extract49, ziziphora clinopodioides58, teucrium stocksianum59, curcumin60 and pistacia integerrima53 have all been shown to inhibit the expression of proinflammatory cytokines to improve airway inflammation, increase the expression levels of AQP1 and AQP5 to reduce pulmonary edema, and thus improve asthma symptoms. The gene discussed is AQP1; the disease is asthma.