Other aspects worth of future investigation could be whether SARS-CoV-2 can trigger autoimmunity to MDA5 through molecular mimicry, epitope spreading, bystander activation, etc., considering that the link between COVID-19 and MDA5 autoimmunity became nuanced when comparing rates of MDA5 positivity to average daily COVID-19 cases. Here, IFIH1 is linked to COVID-19.