Furthermore, KHSRP is involved in the pathophysiological regulation of neuromuscular disorders (Amirouche et al., 2013), obesity (Lin et al., 2014), type II diabetes mellitus (Briata et al., 2016), and cancer (Yuan et al., 2017). The gene discussed is KHSRP; the disease is obesity due to melanocortin 4 receptor deficiency.