No significant differences were observed in patients’ sex, age at PA diagnosis, treatment duration, treatment initiation timing, or germline MEN1 PVs when comparing micro-PRLomas that achieved size reduction versus those that did not, and micro-PRLomas that attained normal PRL levels versus those that did not (Supplementary Tables 2, 3). Here, PRL is linked to prolactin-producing pituitary gland adenoma.