IFNG and diabetes mellitus: Thus, when IFN‐γ secretion is reduced, immune function may be impaired, ultimately increasing the risk of MTB infection.[24, 101, 122] Similarly, in a comparative study by Tsukaguchi et al., it was found that the secretion levels of IFN‐γ in DM‐TB patients were significantly lower than in NDM‐TB patients, and this decrease was more pronounced in poorly controlled DM‐TB patients, indicating a negative correlation between IFN‐γ production and DM control level.[24] Furthermore, to further understand the effect of glycemic control on IFN‐γ secretion, Tsukaguchi et al.