We reviewed and analyzed the studies supporting the two different views, including subjects, sample size, tissues, stimuli, and experimental methods (Table 3).[24, 94, 101, 102, 103, 104, 105, 106, 107, 108, 109] We found that most of the studies supporting the view that “CD4+ T cells in DM‐TB patients exhibit reduced pro‐inflammatory cytokines and increased anti‐inflammatory cytokines, thereby suppressing immune function” were from Asian regions, such as Japan, China, and Indonesia, and the stimuli used were mainly purified protein derivatives (PPD) and BCG. Here, CD4 is linked to tuberculosis.