observed the relationship between CD4+ and CD8+ T cell subsets and FBG or glycated HbA1c levels in DM‐TB patients.[110] They found that the frequency of central memory CD8+ T cells was significantly positively correlated with FBG and HbA1c levels, while the frequency of naïve CD8+ T cells showed a significant negative correlation with FBG and HbA1c levels.[110] This indicates that DM has a certain influence on the frequency of CD8+ T cells. This evidence concerns the gene CD4 and tuberculosis.